The 8th Annual Symposium on ATP1A3 in Disease
Welcome to the 8th Annual Symposium on ATP1A3 in Disease
3-4 October 2019
Registration closes 1 October 2019
The 8th Annual Symposium on ATP1A3 in Disease 2019 will take place 3 - 4 October 2019 at the beautiful and conveniently located Grand Hotel Reykjavík on Iceland.
The host this year is the AHC Association of Iceland supported by an organizing committee that consist of European scientists that have been working on ATP1A3 related diseases for many years.
The ‘ATP1A3 Symposium in Disease’ is an important symposium that focuses on one of the key genes, the ATP1A3 gene that is essential for normal brain functioning. Mutations in the ATP1A3 gene has been linked to several neurological diseases, including Alternating Hemiplegia of Childhood (AHC). The ATP1A3 gene encodes the alpha(a)3 subunit isoform of the sodium pump, an ion pump that is present in all cells of the body and help cells to maintain correct ion balance, to support in-and outflux of molecules in the cell. In the brain, the a 3 isoform is specific to nerve cells, the neurons. In most neurons, the a 3 isoform helps to maintain the resting membrane potential and reset the ion gradient after an action potential. Doing this, the sodium pump uses energy from the cells and is the most energy-consuming ion pump in the brain. Therefore, it is not surprising that mutations that alter the function of such a vital pump, is associated with neurological diseases.
Symposium venue address:
Confirmed Invited Speakers:
- Allison Brashear - School of Medicine Dean, UC Davis Health, California
- David B. Goldstein - Professor, Columbia University, New York
- Francesco Danilo Tiziano - Associate professor, Università Cattolica del Sacro Cuore, Milano, Italy
- Guangping Gao - Professor, University of Massachusetts Medical School, Worcester, Massachusetts
- Helga Birgisdóttir - Artist, CEO and Creator of SMILER, Iceland
- Hreinn Stefánsson - Head of Central Nervous System Division at the company deCODE genetics, Iceland
- Laufey Ýr Sigurðardóttir - Child Neurologist and Epileptologist, University Hospital of Iceland, Reykjavik, Iceland
- Laura Heimgartner, Mother of the boy Dax, who has AHC
- Marisol Sampedro Castaneda - Postdoctoral researcher, The Francis Crick Institute, London, United Kingdom
- Mohamad Mikati - Professor, Duke Institute for Brain Sciences, Durham, North Carolina
- Peter Vangheluwe - Associate professor, Katholieke Universiteit Leuven, Belgium
- Poul Nissen - Professor, Aarhus University, Aarhus, Denmark
- Steven Gray - Associate professor, University of Texas Southwestern Medical Center, Dallas, Texas
This year, we also have the honor of having The President of Iceland, Gudni Th. Johannesson, giving the opening speech at the symposium (if his schedule permits).
Associations & Organizations in attendance:
- AHC Association of Iceland - An association for patients with Alternating Hemiplegia of Childhood, and a non-profit organization offering support for affected children and their families
- AHC Federation of Europe - Finding a treatment for Alternating Hemiplegia of Childhood
Find more information on the symposium website: www.atp1a3symposium2019.org